SUN3

Across TCGA patient cohorts, SUN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,128 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUN3-associated GO terms across cancer lineages are Regulation of DNA replication, tRNA processing, and Regulation of post-translational protein modification. Each is linked with SUN3 in more than 17 cancer types. Because this analysis shows association rather than direction, both SUN3-to-partner and partner-to-SUN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA replication grouped by SUN3-low versus SUN3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUN3→partner) and Y-score (partner→SUN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA replication →	+0.064	+0.286	<.001	<.001	3	18
STAD	tRNA processing →	+0.058	+0.265	<.001	<.001	3	17
STAD	Regulation of post-translational protein modification →	+0.065	+0.207	<.001	<.001	3	17
STAD	Protein localization to nuclear body →	+0.068	+0.249	<.001	<.001	3	17
ESCA	Endosome organization →	+0.073	+0.566	<.001	<.001	3	17
STAD	Ribonucleoside monophosphate biosynthetic process →	+0.054	+0.252	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,128 associations by consensus.

Regulation of DNA replication by SUN3 expression — STAD

Explore this box plot interactively →