SUN2

Across TCGA cell cohorts, SUN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,875 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUN2-associated GO terms across cancer lineages are Nuclear matrix anchoring at nuclear membrane, Nuclear migration along microtubule, and Nuclear matrix organization. Each is linked with SUN2 in more than 18 cancer types. Because this analysis shows association rather than direction, both SUN2-to-partner and partner-to-SUN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear matrix anchoring at nuclear membrane grouped by SUN2-low versus SUN2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUN2→partner) and Y-score (partner→SUN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nuclear matrix anchoring at nuclear membrane →	+0.240	+1.282	<.001	<.001	3	19
LUNG_SCLC	Nuclear migration along microtubule →	+0.189	+1.655	<.001	<.001	3	19
LUNG_SCLC	Nuclear matrix organization →	+0.240	+1.282	<.001	<.001	3	19
KIDNEY	Cerebral cortex radial glia-guided migration →	+0.152	+1.312	<.001	<.001	3	17
LARGE_INTESTINE	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.173	+1.034	<.001	<.001	3	17
KIDNEY	Telencephalon glial cell migration →	+0.152	+1.312	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,875 associations by consensus.

Nuclear matrix anchoring at nuclear membrane by SUN2 expression — LUNG_SCLC

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