SUMO4

Across TCGA patient cohorts, SUMO4 protein abundance is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SUMO4-associated genes across cancer lineages are VCPKMT, RPS6KA5, and PPP4R3A. Each is linked with SUMO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUMO4-to-partner and partner-to-SUMO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SUMO4 versus VCPKMT in PDAC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO4→partner) and Y-score (partner→SUMO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VCPKMT →	+0.485	+0.461	.001	.001	3	1
PDAC	RPS6KA5 →	+0.308	+0.557	.006	.009	3	1
PDAC	PPP4R3A →	+0.382	+0.482	.003	.006	3	1
PDAC	TRIP11 →	+0.454	+0.506	.002	.007	3	1
PDAC	MCF2 →	+0.285	+0.527	.001	.008	3	1
PDAC	IQCH →	+0.488	+0.405	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

SUMO4 vs VCPKMT — PDAC

Explore this scatter interactively →