SUMO4

Across TCGA cell cohorts, SUMO4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,361 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SUMO4-associated GO terms across cancer lineages are Protein deubiquitination, Calcium-independent cell-matrix adhesion, and miRNA processing. Each is linked with SUMO4 in more than 12 cancer types. Because this analysis shows association rather than direction, both SUMO4-to-partner and partner-to-SUMO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein deubiquitination grouped by SUMO4-low versus SUMO4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO4→partner) and Y-score (partner→SUMO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein deubiquitination →	+0.050	+0.125	<.001	.009	2	13
CNS	Calcium-independent cell-matrix adhesion →	+0.206	+0.223	<.001	<.001	3	12
PANCREAS	miRNA processing →	+0.080	+0.110	<.001	<.001	3	11
SOFT_TISSUE	Microtubule polymerization →	+0.085	+0.122	<.001	<.001	3	11
LARGE_INTESTINE	Microtubule nucleation →	+0.125	+0.138	.002	<.001	3	11
CNS	Pre-mRNA catabolic process →	+0.146	+0.269	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,361 associations by consensus.

Protein deubiquitination by SUMO4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →