Across TCGA cell cohorts, SUMO3 mutation is significantly associated with the mutation status of many other genes, with 1,343 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUMO3-associated genes across cancer lineages are NFE2L2, KRT1, and PPP1R13B. Each is linked with SUMO3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SUMO3-to-partner and partner-to-SUMO3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO3→partner) and Y-score (partner→SUMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NFE2L2 →	+4.321	+5.285	.005	.005	1	4
BLOOD_Leukemia	KRT1 →	+4.000	+5.050	.008	.008	1	3
BLOOD_Leukemia	PPP1R13B →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	OR2W3 →	+4.000	+5.050	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	SRC →	+4.954	+4.392	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	MLF2 →	+4.954	+4.392	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,343 associations by consensus.

Exploration

SUMO3 survival (RNA) · tumor vs normal (RNA) · all SUMO3 data types