Across TCGA pan-cancer cohorts, SUMO2P8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SUMO2P8’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where SUMO2P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SUMO2P8 is over-expressed in tumor.
LUAD and COAD are the cancer types where SUMO2P8 tumor–normal differential expression is most reproducible.