SUMO2P6

Across TCGA pan-cancer cohorts, SUMO2P6 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated SUMO2P6 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SUMO2P6 RNA is associated with better overall survival. In most high-consensus cancer types, elevated SUMO2P6 expression acts as an unfavorable survival marker, although some lineages such as CESC and BLCA show a favorable association.

CESC, BLCA, and SKCM are the cancer types where SUMO2P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Quartile	II,III,IV	0.933	0.473	.005	38	view →
BLCA	OS	Quartile	All	0.639	0.301	.011	36	view →
SKCM	OS	Median	All	0.388	0.275	.005	33	view →
LUSC	DFS	Tertile	III,IV	0.510	0.816	.001	32	view →
HNSC	DFS	Tertile	III,IV	0.444	0.204	.002	26	view →
LIHC	OS	Quartile	II,III,IV	0.316	0.614	.003	26	view →
LAML	DFS	Quartile	All	0.642	0.207	.005	24	view →
LUAD	OS	Median	III,IV	0.502	0.773	.005	17	view →
KIRC	DFS	Quartile	All	0.735	0.555	.015	14	view →
KIRP	DFS	Quartile	II,III,IV	0.198	0.774	.005	11	view →
KICH	DFS	Tertile	All	0.585	0.944	.022	10	view →
OV	OS	Quartile	IV	0.586	0.275	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

SUMO2P6–CESC (OS)

Open the CESC breakdown →