Across TCGA patient cohorts, SUMO2P21 mutation is significantly associated with the RNA expression of many other genes, with 477 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUMO2P21-associated genes across cancer lineages are USP9YP2, MTCO1P56, and MS4A13. Each is linked with SUMO2P21 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUMO2P21-to-partner and partner-to-SUMO2P21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO2P21→partner) and Y-score (partner→SUMO2P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP9YP2 →	+0.022	+5.481	<.001	<.001	3	2
SKCM	MTCO1P56 →	+0.180	+4.224	<.001	.002	3	2
COAD	MS4A13 →	+0.192	+5.283	.005	.006	3	1
COAD	MIR646 →	+0.557	+5.212	<.001	.007	3	1
COAD	LINC01665 →	+0.202	+5.435	<.001	.005	3	1
COAD	LINC02403 →	+0.322	+5.893	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 477 associations by consensus.

Exploration

SUMO2P21 survival (RNA) · tumor vs normal (RNA) · all SUMO2P21 data types