Across TCGA patient cohorts, SUMO2P21 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUMO2P21-associated genes across cancer lineages are PCNA, VHL, and Cyclin-B1. Each is linked with SUMO2P21 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUMO2P21-to-partner and partner-to-SUMO2P21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO2P21→partner) and Y-score (partner→SUMO2P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.243	+3.169	.041	.020	3	1
UCEC	VHL →	-1.004	-3.169	.007	.020	3	1
UCEC	Cyclin-B1 →	+0.780	+3.169	.011	.020	2	1
UCEC	JNK2 →	+0.305	+3.169	.005	.020	1	1
UCEC	MEK1 →	+0.594	+3.169	.003	.020	1	1
UCEC	Rictor_pT1135 →	-0.134	-3.169	.017	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

SUMO2P21 survival (RNA) · tumor vs normal (RNA) · all SUMO2P21 data types