SUMO2P15

Across TCGA pan-cancer cohorts, SUMO2P15 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of SUMO2P15’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where SUMO2P15 RNA is repressed in tumor relative to normal tissue. In most cancer types SUMO2P15 is over-expressed in tumor, although a few such as UCEC and BRCA show the opposite, repressed pattern.

UCEC, BRCA, and READ are the cancer types where SUMO2P15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SUMO2P15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.425	.004	6	view →
BRCA	All	All	−0.286	<.001	6	view →
READ	All	III,IV	−0.285	.024	3	view →
LUSC	All	All	−0.157	.002	3	view →
LUAD	Female	II,III,IV	−0.254	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

SUMO2P15–UCEC

Open the UCEC breakdown →