Across TCGA patient cohorts, SUMO2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,627 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SUMO2-associated genes across cancer lineages are NUP85, DDX42, and CEP95. Each is linked with SUMO2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SUMO2-to-partner and partner-to-SUMO2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO2→partner) and Y-score (partner→SUMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUP85 →	+0.510	+0.374	.007	.009	3	6
LSCC	DDX42 →	+0.421	+0.226	<.001	<.001	3	5
LSCC	CEP95 →	+0.533	+0.245	<.001	<.001	3	5
LSCC	NT5C →	+0.662	+0.324	<.001	<.001	3	4
GBM	CD93 →	-0.680	-0.288	.001	.001	3	4
LSCC	LSM8 →	+0.630	+0.365	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,627 associations by consensus.

Exploration

SUMO2 survival (RNA) · tumor vs normal (RNA) · all SUMO2 data types