Across TCGA patient cohorts, SUMO2 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,981 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SUMO2-associated proteins across cancer lineages are PPP1R8, SMNDC1, and SAP18. Each is linked with SUMO2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SUMO2-to-partner and partner-to-SUMO2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO2→partner) and Y-score (partner→SUMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R8 →	+0.303	+0.478	<.001	<.001	3	9
GBM	SMNDC1 →	+0.294	+0.288	<.001	<.001	3	8
GBM	SAP18 →	+0.383	+0.459	<.001	<.001	3	7
GBM	SRSF2 →	+0.267	+0.453	<.001	<.001	3	7
BRCA	SRSF3 →	+0.282	+0.740	<.001	<.001	3	7
GBM	POLDIP3 →	+0.510	+0.488	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,981 associations by consensus.

Exploration

SUMO2 survival (RNA) · tumor vs normal (RNA) · all SUMO2 data types