Across TCGA patient cohorts, SUMO2 mutation is significantly associated with the RNA expression of many other genes, with 910 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUMO2-associated genes across cancer lineages are RN7SL134P, HIKESHI, and DSN1. Each is linked with SUMO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUMO2-to-partner and partner-to-SUMO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO2→partner) and Y-score (partner→SUMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.125	+2.599	.006	.009	3	2
UCEC	HIKESHI →	+0.676	+3.364	<.001	.004	3	1
UCEC	DSN1 →	+0.748	+3.480	.002	.002	3	1
UCEC	HIRIP3 →	+0.631	+3.202	.001	.009	3	1
UCEC	CWC15 →	+0.506	+3.459	.005	.005	3	1
UCEC	CCT5 →	+0.912	+3.470	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 910 associations by consensus.

Exploration

SUMO2 survival (RNA) · tumor vs normal (RNA) · all SUMO2 data types