Across TCGA patient cohorts, SUMO2 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUMO2-associated genes across cancer lineages are Monocytes, Endothelial cells, and lymphatic Endothelial cells. Each is linked with SUMO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUMO2-to-partner and partner-to-SUMO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO2→partner) and Y-score (partner→SUMO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Monocytes →	+0.014	+5.225	<.001	.034	3	1
UCEC	Endothelial cells →	-0.040	-2.279	.034	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.048	.019	3	1
UCEC	MEP →	+0.036	+2.332	.009	.020	3	1
UCEC	mv Endothelial cells →	-0.027	-2.311	.022	.036	3	1
UCEC	Plasma cells →	-0.022	-2.279	.043	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

SUMO2 survival (RNA) · tumor vs normal (RNA) · all SUMO2 data types