SUMF1

Across TCGA patient cohorts, SUMF1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,448 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SUMF1-associated genes across cancer lineages are COL1A1, LOXL2, and ACSS1. Each is linked with SUMF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SUMF1-to-partner and partner-to-SUMF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SUMF1 versus COL1A1 in GBM, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMF1→partner) and Y-score (partner→SUMF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	COL1A1 →	+1.995	+0.625	<.001	<.001	3	6
PDAC	LOXL2 →	+1.142	+0.305	<.001	<.001	3	5
PDAC	ACSS1 →	-0.849	-0.354	<.001	<.001	3	5
UCEC	CTHRC1 →	+1.154	+0.353	<.001	<.001	3	5
GBM	ALPK2 →	+1.427	+0.691	<.001	<.001	3	5
GBM	PLAUR →	+1.074	+0.608	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,448 associations by consensus.

SUMF1 vs COL1A1 — GBM

Explore this scatter interactively →