SULT4A1

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SULT4A1 mutation is significantly associated with the drug of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SULT4A1-associated genes across cancer lineages are 123138, 743380, and IRAK4_4710. Each is linked with SULT4A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT4A1-to-partner and partner-to-SULT4A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123138 grouped by SULT4A1-low versus SULT4A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT4A1→partner) and Y-score (partner→SULT4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINE123138 →+0.324+2.649.028.04631
LARGE_INTESTINE743380 →+0.632+2.649.021.04631
LARGE_INTESTINEIRAK4_4710 →+0.369+2.649.043.04611
LARGE_INTESTINEJAK1_8709 →+0.428+2.649.030.04611
LARGE_INTESTINE741909 →+0.702+2.649.007.04611
LARGE_INTESTINENSC-207895 →+0.462+2.786.033.03711
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

123138 by SULT4A1 expression — LARGE_INTESTINE

Box plot of 123138 in SULT4A1-low vs SULT4A1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration