SULT2B1

Across TCGA patient cohorts, SULT2B1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT2B1-associated genes across cancer lineages are eEF2, A-Raf_pS299, and ERK2. Each is linked with SULT2B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT2B1-to-partner and partner-to-SULT2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SULT2B1-low versus SULT2B1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT2B1→partner) and Y-score (partner→SULT2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.507	+3.321	<.001	.009	3	1
UCEC	A-Raf_pS299 →	-0.145	-3.584	.004	.002	3	1
UCEC	ERK2 →	+0.210	+2.906	.010	.001	3	1
UCEC	GAPDH →	+0.493	+1.700	.030	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.201	-2.459	.004	.019	3	1
UCEC	JNK2 →	+0.222	+2.179	.008	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

eEF2 by SULT2B1 expression — UCEC

Explore this box plot interactively →