SULT2B1

Across TCGA cell cohorts, SULT2B1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SULT2B1-associated genes across cancer lineages are CDRT15L2, ANKRD66, and OR6N1. Each is linked with SULT2B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT2B1-to-partner and partner-to-SULT2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDRT15L2 grouped by SULT2B1-low versus SULT2B1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT2B1→partner) and Y-score (partner→SULT2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CDRT15L2 →	+0.013	+5.781	<.001	.001	3	1
BREAST	ANKRD66 →	+0.030	+5.781	<.001	.001	3	1
BLOOD_Leukemia	OR6N1 →	+0.220	+4.060	<.001	.003	3	1
BLOOD_Leukemia	HMX1 →	+0.360	+4.234	.004	.003	3	1
LARGE_INTESTINE	MDGA2 →	+0.228	+3.854	<.001	.006	3	1
LARGE_INTESTINE	LRRC3B →	+0.022	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CDRT15L2 by SULT2B1 expression — BREAST

Explore this box plot interactively →