Across TCGA pan-cancer cohorts, SULT1C4 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SULT1C4 data layer compared with 27 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SULT1C4 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated SULT1C4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, LIHC, and SKCM are the cancer types where SULT1C4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.616	.004	36	view →
LIHC	OS	Median	All	0.167	0.704	.041	3	view →
SKCM	DFS	Median	II,III,IV	0.803	0.557	.030	3	view →
LUSC	DFS	Median	All	1.000	0.368	.038	2	view →
COAD	OS	Median	All	0.598	0.872	.028	2	view →
BLCA	DFS	Median	IV	1.000	0.197	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: SULT1C4 tumor-vs-normal RNA expression · all SULT1C4 data types