Across TCGA pan-cancer cohorts, SULT1C4 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SULT1C4 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SULT1C4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SULT1C4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC and LUAD are the cancer types where SULT1C4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.879	0.627	.010	15	view →
LUAD	DFS	Quartile	All	0.364	0.880	.007	11	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SULT1C4 tumor-vs-normal RNA expression · all SULT1C4 data types