Across TCGA patient cohorts, SULT1C4 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1C4-associated genes across cancer lineages are TFRC, c-Met_pY1235, and EGFR_pY1068. Each is linked with SULT1C4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1C4-to-partner and partner-to-SULT1C4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1C4→partner) and Y-score (partner→SULT1C4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.639	+3.584	.001	.002	3	2
UCEC	c-Met_pY1235 →	+0.085	+2.331	.002	.003	3	2
UCEC	EGFR_pY1068 →	-0.229	-1.678	.017	.023	3	1
UCEC	EGFR →	-0.202	-2.584	<.001	.010	3	1
UCEC	FoxM1 →	+0.218	+2.087	.027	.005	3	1
UCEC	JNK_pT183_Y185 →	-0.191	-2.700	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

SULT1C4 survival (RNA) · tumor vs normal (RNA) · all SULT1C4 data types