Across TCGA patient cohorts, SULT1C3 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1C3-associated genes across cancer lineages are STAT3_pY705, FOXO3a_pS318_S321, and JNK_pT183_Y185. Each is linked with SULT1C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1C3-to-partner and partner-to-SULT1C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1C3→partner) and Y-score (partner→SULT1C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.542	-2.999	<.001	.035	3	2
UCEC	FOXO3a_pS318_S321 →	-0.164	-2.990	.016	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.238	-3.156	.010	.020	3	1
UCEC	JNK2 →	+0.418	+3.026	<.001	.018	3	1
UCEC	mTOR_pS2448 →	-0.189	-3.169	.021	.020	3	1
UCEC	N-Ras →	-0.191	-3.156	.003	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

SULT1C3 survival (RNA) · tumor vs normal (RNA) · all SULT1C3 data types