Across TCGA patient cohorts, SULT1C2 mutation is significantly associated with the RNA expression of many other genes, with 391 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1C2-associated genes across cancer lineages are ELOA3BP, RPL22P6, and OR7E110P. Each is linked with SULT1C2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SULT1C2-to-partner and partner-to-SULT1C2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1C2→partner) and Y-score (partner→SULT1C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ELOA3BP →	+0.007	+4.351	<.001	.004	3	3
COAD	RPL22P6 →	+0.083	+4.721	<.001	.004	3	2
SKCM	OR7E110P →	+0.085	+2.332	.008	.008	3	2
UCEC	RAPGEF1 →	+0.678	+3.617	<.001	.001	3	2
UCEC	NR1D1 →	+0.526	+2.807	.006	.003	3	2
UCEC	CHAC1 →	+0.854	+2.818	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 391 associations by consensus.

Exploration

SULT1C2 survival (RNA) · tumor vs normal (RNA) · all SULT1C2 data types