Across TCGA patient cohorts, SULT1C2 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1C2-associated genes across cancer lineages are mTOR_pS2448, JNK2, and MEK1. Each is linked with SULT1C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1C2-to-partner and partner-to-SULT1C2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1C2→partner) and Y-score (partner→SULT1C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.165	-2.986	.021	.035	3	2
UCEC	JNK2 →	+0.220	+3.584	.022	.002	3	1
UCEC	MEK1 →	+0.696	+3.584	<.001	.002	3	1
UCEC	Notch1 →	+0.237	+2.459	<.001	.020	3	1
UCEC	Caspase-7-cleavedD198 →	+0.692	+3.019	.015	.019	3	1
UCEC	Chk2 →	-0.235	-2.459	.038	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

SULT1C2 survival (RNA) · tumor vs normal (RNA) · all SULT1C2 data types