SULT1B1

Across TCGA patient cohorts, SULT1B1 mutation is significantly associated with the RNA expression of many other genes, with 1,939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1B1-associated genes across cancer lineages are OR5AC2, RNU1-154P, and MIR6870. Each is linked with SULT1B1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SULT1B1-to-partner and partner-to-SULT1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5AC2 grouped by SULT1B1-low versus SULT1B1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1B1→partner) and Y-score (partner→SULT1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	OR5AC2 →	+0.414	+4.733	<.001	.004	3	3
GBM	RNU1-154P →	+0.400	+4.108	<.001	.003	3	2
GBM	MIR6870 →	+0.973	+4.874	<.001	<.001	3	2
SKCM	EEF1E1-BLOC1S5 →	+0.051	+3.351	<.001	.008	3	2
BRCA	PRAMEF25 →	+0.009	+7.731	<.001	.009	3	2
LUAD	LINC00686 →	+0.115	+3.376	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,939 associations by consensus.

OR5AC2 by SULT1B1 expression — LUSC

Explore this box plot interactively →