Across TCGA pan-cancer cohorts, SULT1A4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SULT1A4’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SULT1A4 RNA is repressed in tumor relative to normal tissue. In most cancer types SULT1A4 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

BLCA, STAD, and LUAD are the cancer types where SULT1A4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SULT1A4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Female	III,IV	−0.017	.015	7	view →
STAD	Female	All	+0.030	.049	2	view →
LUAD	All	III,IV	+0.021	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SULT1A4 RNA expression & survival · all SULT1A4 data types