SULT1A3

Across TCGA pan-cancer cohorts, SULT1A3 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated SULT1A3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SULT1A3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SULT1A3 expression acts as an unfavorable survival marker, although some lineages such as BLCA and CESC show a favorable association.

KIRC, BLCA, and KIRP are the cancer types where SULT1A3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.511	0.715	<.001	87	view →
BLCA	DFS	Quartile	III,IV	0.405	0.201	<.001	71	view →
KIRP	DFS	Median	III,IV	0.423	0.693	.009	54	view →
COAD	DFS	Tertile	All	0.665	0.828	.001	38	view →
LGG	DFS	Median	All	0.664	0.795	<.001	36	view →
CESC	OS	Tertile	All	0.678	0.443	.005	18	view →
DLBC	OS	Median	All	0.400	0.948	.013	11	view →
ACC	DFS	Median	III,IV	0.479	0.758	.030	11	view →
SKCM	OS	Median	II,III,IV	0.801	0.875	.009	10	view →
CHOL	OS	Quartile	All	0.792	0.145	.041	6	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	6	view →
SCLC	OS	Median	II,III,IV	0.533	0.732	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

SULT1A3–KIRC (DFS)

Open the KIRC breakdown →