SULT1A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SULT1A2 mutation is significantly associated with the RNA expression of many other genes, with 312 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1A2-associated genes across cancer lineages are MTND5P35, RNU6-668P, and RNU6-1133P. Each is linked with SULT1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1A2-to-partner and partner-to-SULT1A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1A2→partner) and Y-score (partner→SULT1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMTND5P35 →+0.035+5.539<.001.00432
UCECRNU6-668P →+0.215+3.034.002.00832
UCECRNU6-1133P →+0.315+3.072<.001.00232
UCECUSP37P1 →+0.052+4.010<.001.00731
UCECRNU6-94P →+0.773+3.606.005.00131
UCECSTMN1P1 →+0.479+3.302<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 312 associations by consensus.

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