Across TCGA patient cohorts, SULT1A2 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1A2-associated genes across cancer lineages are Annexin-1, C-Raf, and FOXO3a_pS318_S321. Each is linked with SULT1A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1A2-to-partner and partner-to-SULT1A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1A2→partner) and Y-score (partner→SULT1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.794	+2.827	.003	.035	3	2
UCEC	C-Raf →	+0.163	+3.000	.029	.036	3	2
UCEC	FOXO3a_pS318_S321 →	-0.160	-3.321	.014	.010	3	1
UCEC	PAI-1 →	-0.353	-3.321	.049	.010	3	1
UCEC	Shc_pY317 →	-0.189	-3.000	.017	.036	3	1
UCEC	c-Met_pY1235 →	+0.098	+2.817	.011	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

SULT1A2 survival (RNA) · tumor vs normal (RNA) · all SULT1A2 data types