Across TCGA patient cohorts, SULT1A1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SULT1A1-associated genes across cancer lineages are EGFR_pY1068, Heregulin, and JNK2. Each is linked with SULT1A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1A1-to-partner and partner-to-SULT1A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1A1→partner) and Y-score (partner→SULT1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.281	-2.459	.020	.020	3	1
UCEC	Heregulin →	-0.149	-3.169	.012	.019	3	1
UCEC	JNK2 →	+0.378	+3.196	<.001	.009	3	1
UCEC	p62 Lck ligand →	+0.372	+3.009	.018	.019	3	1
UCEC	TIGAR →	+0.154	+2.486	.037	.011	3	1
UCEC	VHL →	-0.813	-3.000	.013	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

SULT1A1 survival (RNA) · tumor vs normal (RNA) · all SULT1A1 data types