Across TCGA cell cohorts, SULT1A1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SULT1A1-associated genes across cancer lineages are IFNA4, PPIAL4F, and FAM240A. Each is linked with SULT1A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1A1-to-partner and partner-to-SULT1A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1A1→partner) and Y-score (partner→SULT1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IFNA4 →	+0.160	+4.321	<.001	.009	3	1
CNS	PPIAL4F →	+0.098	+4.832	<.001	.002	3	1
CNS	FAM240A →	+0.012	+4.169	.004	.008	3	1
LARGE_INTESTINE	MROH2B →	+0.006	+5.415	<.001	.004	3	1
CNS	CYP4A22 →	+0.018	+4.345	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SULT1A1 survival (RNA) · tumor vs normal (RNA) · all SULT1A1 data types