Across TCGA patient cohorts, SULF2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,900 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SULF2-associated genes across cancer lineages are TGFB3, CDH11, and SORCS2. Each is linked with SULF2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SULF2-to-partner and partner-to-SULF2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULF2→partner) and Y-score (partner→SULF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TGFB3 →	+1.050	+0.520	<.001	.003	3	7
OV	CDH11 →	+1.326	+0.672	<.001	<.001	3	7
CCRCC	SORCS2 →	+1.578	+0.700	<.001	<.001	3	7
CCRCC	GFPT2 →	+1.763	+0.622	<.001	<.001	3	7
OV	CLMP →	+1.182	+0.665	<.001	<.001	3	7
BRCA	MEIS3 →	+1.341	+0.650	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,900 associations by consensus.

Exploration

SULF2 survival (RNA) · tumor vs normal (RNA) · all SULF2 data types