Across TCGA cell cohorts, SULF2 mutation is significantly associated with the RNA expression of many other genes, with 198 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SULF2-associated genes across cancer lineages are MAGEB4, GPR3, and TXLNA. Each is linked with SULF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULF2-to-partner and partner-to-SULF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULF2→partner) and Y-score (partner→SULF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.009	+3.000	<.001	.003	3	2
LARGE_INTESTINE	GPR3 →	+0.889	+3.364	<.001	.002	3	2
LARGE_INTESTINE	TXLNA →	+0.640	+3.364	.003	.002	3	2
BLOOD_Leukemia	CST2 →	+0.227	+2.889	.001	.002	3	2
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
LUNG_NSCLC_LUAD	CARTPT →	+0.008	+3.681	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 198 associations by consensus.

Exploration

SULF2 survival (RNA) · tumor vs normal (RNA) · all SULF2 data types