SULF1

Across TCGA pan-cancer cohorts, SULF1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SULF1 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SULF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SULF1 expression acts as an unfavorable survival marker.

COAD, CCRCC, and LUAD are the cancer types where SULF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	0.829	1.000	.027	30	view →
CCRCC	DFS	Quartile	II,III,IV	0.066	0.928	.010	15	view →
LUAD	OS	Median	II,III,IV	0.449	0.893	.023	8	view →
PDAC	DFS	Tertile	IV	0.250	0.934	.024	8	view →
GBM	OS	Median	All	0.762	0.957	.006	7	view →
LSCC	DFS	Median	All	0.606	0.800	.014	6	view →
HNSC	DFS	Median	IV	0.528	0.804	.003	5	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SULF1–COAD (DFS)

Open the COAD breakdown →