SULF1

Across TCGA patient cohorts, SULF1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,370 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SULF1-associated genes across cancer lineages are COL1A1, FN1, and INHBA. Each is linked with SULF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SULF1-to-partner and partner-to-SULF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SULF1 versus COL1A1 in OV, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULF1→partner) and Y-score (partner→SULF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL1A1 →	+2.760	+0.898	<.001	<.001	3	10
OV	FN1 →	+2.523	+1.063	<.001	<.001	3	10
OV	INHBA →	+2.742	+1.253	<.001	<.001	3	10
CCRCC	ISLR →	+1.649	+0.959	<.001	<.001	3	10
OV	ADAMTS12 →	+1.911	+1.163	<.001	<.001	3	10
OV	OLFML2B →	+1.858	+1.245	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,370 associations by consensus.

SULF1 vs COL1A1 — OV

Explore this scatter interactively →