SULF1

Across TCGA cell cohorts, SULF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,809 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SULF1-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Response to hydrostatic pressure, and Cytoplasmic translation. Each is linked with SULF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SULF1-to-partner and partner-to-SULF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by SULF1-low versus SULF1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SULF1→partner) and Y-score (partner→SULF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.108	+2.072	<.001	<.001	3	10
SKIN	Response to hydrostatic pressure →	+0.189	+2.905	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.093	+1.795	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.070	+1.934	<.001	.008	3	9
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.945	.001	.003	2	9
UPPER_AERODIGESTIVE_TRACT	Aerobic electron transport chain →	+0.097	+1.657	<.001	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,809 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by SULF1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →