SUGT1

Across TCGA pan-cancer cohorts, SUGT1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SUGT1 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SUGT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SUGT1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where SUGT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.830	1.000	.003	13	view →
HNSC	DFS	Median	III,IV	0.688	0.859	.017	12	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SUGT1–LSCC (DFS)

Open the LSCC breakdown →