SUGP2

Across TCGA pan-cancer cohorts, SUGP2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SUGP2 data layer compared with 30 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SUGP2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SUGP2 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

HNSC, PDAC, and GBM are the cancer types where SUGP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.933	0.992	.024	13	view →
PDAC	OS	Quartile	III,IV	0.184	0.604	.010	10	view →
GBM	OS	Quartile	All	0.650	0.294	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SUGP2–HNSC (OS)

Open the HNSC breakdown →