SUGP2

Across TCGA cell cohorts, SUGP2 mutation is significantly associated with the RNA expression of many other genes, with 52 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUGP2-associated genes across cancer lineages are SPATA31A7, GSG1L2, and USP17L11. Each is linked with SUGP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUGP2-to-partner and partner-to-SUGP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31A7 grouped by SUGP2-low versus SUGP2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUGP2→partner) and Y-score (partner→SUGP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SPATA31A7 →	+0.076	+4.794	<.001	.001	3	2
BLOOD_Leukemia	GSG1L2 →	+0.028	+3.969	<.001	.009	3	2
OVARY	USP17L11 →	+0.044	+5.339	<.001	<.001	3	2
BLOOD_Myeloma	ZSWIM2 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1QA →	+0.206	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	SPRR2G →	+0.350	+4.191	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

SPATA31A7 by SUGP2 expression — STOMACH

Explore this box plot interactively →