SUGP1

Across TCGA cell cohorts, SUGP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,248 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUGP1-associated GO terms across cancer lineages are Negative regulation of protein localization to chromatin, Negative regulation of DNA-templated transcription, elongation, and Negative regulation of transcription elongation by RNA polymerase II. Each is linked with SUGP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SUGP1-to-partner and partner-to-SUGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to chromatin grouped by SUGP1-low versus SUGP1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUGP1→partner) and Y-score (partner→SUGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of protein localization to chromatin →	+0.163	+0.988	<.001	<.001	3	17
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.122	+0.568	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription elongation by RNA polymerase II →	+0.129	+0.598	<.001	<.001	3	17
SOFT_TISSUE	Regulation of protein sumoylation →	+0.126	+0.859	<.001	<.001	3	16
STOMACH	Regulation of protein localization to chromatin →	+0.127	+0.798	.001	.003	2	17
BONE	Epigenetic regulation of gene expression →	+0.095	+0.849	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

Negative regulation of protein localization to chromatin by SUGP1 expression — URINARY_TRACT

Explore this box plot interactively →