SUDS3

Across TCGA pan-cancer cohorts, SUDS3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SUDS3 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SUDS3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SUDS3 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where SUDS3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.971	0.684	<.001	43	view →
HNSC	DFS	Median	All	0.534	0.733	.007	28	view →
CCRCC	OS	Tertile	All	0.937	0.779	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SUDS3–LSCC (OS)

Open the LSCC breakdown →