SUDS3

Across TCGA patient cohorts, SUDS3 mutation is significantly associated with the RNA expression of many other genes, with 2,552 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUDS3-associated genes across cancer lineages are RNA5SP24, RNA5SP412, and MIR4650-1. Each is linked with SUDS3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUDS3-to-partner and partner-to-SUDS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP24 grouped by SUDS3-low versus SUDS3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUDS3→partner) and Y-score (partner→SUDS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP24 →	+0.504	+1.976	<.001	.007	3	3
UCEC	RNA5SP412 →	+0.645	+2.230	<.001	<.001	3	2
LUSC	MIR4650-1 →	+0.530	+5.625	<.001	.004	3	2
BRCA	RN7SL261P →	+0.230	+4.396	<.001	.002	3	1
COAD	RNU6-572P →	+0.442	+7.741	<.001	.009	3	1
UCEC	SRXN1 →	+0.384	+2.606	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,552 associations by consensus.

RNA5SP24 by SUDS3 expression — UCEC

Explore this box plot interactively →