SUCLG2

Across TCGA pan-cancer cohorts, SUCLG2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SUCLG2 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SUCLG2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SUCLG2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, UCEC, and LSCC are the cancer types where SUCLG2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.982	0.434	.004	25	view →
UCEC	OS	Tertile	II,III,IV	0.648	1.000	.045	4	view →
LSCC	DFS	Tertile	All	0.620	0.808	.042	1	view →
PDAC	DFS	Quartile	All	0.791	0.696	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SUCLG2–CCRCC (DFS)

Open the CCRCC breakdown →