SUCLG2

Across TCGA patient cohorts, SUCLG2 mutation is significantly associated with the RNA expression of many other genes, with 755 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUCLG2-associated genes across cancer lineages are RNA5SP417, MIR199B, and TRAJ11. Each is linked with SUCLG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUCLG2-to-partner and partner-to-SUCLG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP417 grouped by SUCLG2-low versus SUCLG2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUCLG2→partner) and Y-score (partner→SUCLG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNA5SP417 →	+0.360	+6.608	<.001	.001	3	3
HNSC	MIR199B →	+0.339	+5.182	<.001	.007	3	2
UCEC	TRAJ11 →	+0.361	+1.813	.008	.009	3	2
UCEC	RNA5SP222 →	+0.217	+3.292	<.001	.003	3	2
UCEC	TBRG1 →	+0.335	+3.732	.002	<.001	3	2
UCEC	RNF166 →	+0.408	+2.711	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 755 associations by consensus.

RNA5SP417 by SUCLG2 expression — HNSC

Explore this box plot interactively →