SUCLG2

Across TCGA cell cohorts, SUCLG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,372 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SUCLG2-associated GO terms across cancer lineages are Succinate metabolic process, Monocarboxylic acid catabolic process, and Lipid catabolic process. Each is linked with SUCLG2 in more than 14 cancer types. Because this analysis shows association rather than direction, both SUCLG2-to-partner and partner-to-SUCLG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Succinate metabolic process grouped by SUCLG2-low versus SUCLG2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SUCLG2→partner) and Y-score (partner→SUCLG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Succinate metabolic process →	+0.166	+1.087	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Monocarboxylic acid catabolic process →	+0.068	+0.699	.005	.009	3	9
BONE	Lipid catabolic process →	+0.051	+1.257	<.001	<.001	3	9
LUNG_SCLC	Succinyl-CoA catabolic process →	+0.158	+1.311	<.001	.001	3	9
OESOPHAGUS	Tricarboxylic acid cycle →	+0.086	+0.908	.004	.006	2	9
UPPER_AERODIGESTIVE_TRACT	NADPH regeneration →	+0.107	+0.807	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

Succinate metabolic process by SUCLG2 expression — BONE

Explore this box plot interactively →