SUCLG2

Across TCGA cell cohorts, SUCLG2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUCLG2-associated genes across cancer lineages are OR51T1, GSG1L2, and ITGAD. Each is linked with SUCLG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUCLG2-to-partner and partner-to-SUCLG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by SUCLG2-low versus SUCLG2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUCLG2→partner) and Y-score (partner→SUCLG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	ITGAD →	+0.009	+2.925	.003	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.030	+5.029	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR51T1 by SUCLG2 expression — BLOOD_Leukemia

Explore this box plot interactively →