Across TCGA pan-cancer cohorts, SUCLA2P2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SUCLA2P2’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where SUCLA2P2 RNA is repressed in tumor relative to normal tissue. In most cancer types SUCLA2P2 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
STAD are the cancer types where SUCLA2P2 tumor–normal differential expression is most reproducible.