SUCLA2

Across TCGA patient cohorts, SUCLA2 mutation is significantly associated with the RNA expression of many other genes, with 2,767 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUCLA2-associated genes across cancer lineages are MIR3661, BPNT2P, and RNU6-701P. Each is linked with SUCLA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SUCLA2-to-partner and partner-to-SUCLA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3661 grouped by SUCLA2-low versus SUCLA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUCLA2→partner) and Y-score (partner→SUCLA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3661 →	+0.753	+2.064	<.001	.001	3	3
READ	BPNT2P →	+0.088	+5.096	<.001	.002	3	2
READ	RNU6-701P →	+0.600	+4.462	<.001	.001	3	2
READ	MIR8064 →	+0.731	+4.142	<.001	.004	3	2
UCEC	TUBGCP5 →	+0.528	+2.617	<.001	<.001	3	2
UCEC	ZNF234 →	+0.446	+2.609	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,767 associations by consensus.

MIR3661 by SUCLA2 expression — UCEC

Explore this box plot interactively →