Across TCGA pan-cancer cohorts, SUCLA2-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SUCLA2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SUCLA2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SUCLA2-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and PAAD show a favorable association.

ACC, COAD, and ESCA are the cancer types where SUCLA2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Quartile	II,III,IV	0.222	0.795	<.001	57	view →
COAD	DFS	Tertile	All	0.573	0.814	<.001	40	view →
ESCA	DFS	Tertile	All	0.351	0.596	.001	38	view →
BRCA	OS	Median	IV	0.470	0.992	<.001	37	view →
KIRP	OS	Median	All	0.968	0.895	.002	31	view →
SKCM	OS	Quartile	III,IV	0.301	0.571	.002	25	view →
PAAD	OS	Quartile	All	0.699	0.334	<.001	22	view →
UVM	OS	Median	All	0.454	0.736	.008	21	view →
CHOL	DFS	Tertile	All	0.809	0.140	.005	20	view →
LAML	DFS	Quartile	All	0.365	0.735	.013	18	view →
LIHC	OS	Quartile	All	0.473	0.727	.009	14	view →
LUSC	OS	Tertile	All	0.606	0.388	.023	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

Exploration

Same gene, other analysis: SUCLA2-AS1 tumor-vs-normal RNA expression · all SUCLA2-AS1 data types