SUB1P3

Across TCGA pan-cancer cohorts, SUB1P3 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SUB1P3 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SUB1P3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SUB1P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and COAD show a favorable association.

SKCM, UVM, and LIHC are the cancer types where SUB1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	III,IV	0.615	0.356	<.001	85	view →
UVM	OS	Quartile	III,IV	0.255	1.000	.007	41	view →
LIHC	DFS	Quartile	All	0.399	0.613	<.001	37	view →
STAD	OS	Median	II,III,IV	0.435	0.665	.005	33	view →
COAD	DFS	Quartile	II,III,IV	0.689	0.423	.004	27	view →
CESC	OS	Median	All	0.864	0.728	.002	24	view →
THCA	DFS	Tertile	All	0.890	0.754	.015	23	view →
BRCA	DFS	Tertile	II,III,IV	0.858	0.921	.005	21	view →
PAAD	OS	Quartile	II,III,IV	0.774	0.333	<.001	21	view →
READ	DFS	Tertile	II,III,IV	0.941	0.606	.005	21	view →
SARC	OS	Tertile	All	0.758	0.909	.001	16	view →
KIRC	DFS	Tertile	II,III,IV	0.843	0.624	.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SUB1P3–SKCM (DFS)

Open the SKCM breakdown →